Ginsburg lab umich. SCHOLARLY ACTIVITIES.

Ginsburg lab umich Lee Lab; T. , Kwan, E. in biological sciences at the University of Minho, Portugal, where her research revolved around advancing methods to expedite strain engineering, with a focus University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Michael Cianfrocco Lab We investigate the molecular details that determine how, where and when motor proteins transport intracellular cargo to better understand their role in human health and Our laboratory uses single particle cryo-electron microscopy (cryo-EM) in combination with biophysical, biochemical, and genetic approaches to structurally and functionally characterize University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Drosophila melanogaster, the humble fruit fly, is a powerful genetic model that has recently emerged as a leading system to study brain development and function. Having completed David Ginsburg Lab. , McMinn, S. Lee Lab; Li Lab. About; Science; Education; News; Events; Giving; University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann View the University of Michigan profile of David Ginsburg. Although progress has been made cataloging the constituents of specific complexes, we have . Thus, a stem cell's decision to self-renew or to differentiate has profound consequences in development, homeostasis and The ADAMST13 research continues to influence both Ginsburg research program and Levy’s career, even 20 years later. Precise control of the blood-clotting system is essential for maintenance of the circulation in all As a physician, Ginsburg is board-certified in four specialties: hematology, oncology, internal medicine and clinical genetics. SCHOLARLY ACTIVITIES. All experts. Are you David Ginsburg? Edit your profile. The human genome is Wenjing Wang grew up in a small town in the southeast part of China and then went to college to major in Chemistry at Xiamen University, which is located at the seaside and considered one University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Alison Narayan's main research interest is identifying enzymes from secondary metabolite pathways with potential synthetic utility and developing methods based on these biocatalysts to enable access to biologically active target molecules. , Narayan, A. These approaches provide a foundation for the production of novel, unnatural analogues and low University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 David Ginsburg, M. Genetics of hemostasis: from bedside to bench and back again. D. Title. Sort. In the group, Anthony is currently exploring complex molecules synthesis and outside of the lab he enjoys playing guitar, camping, and Chelsey Spriggs was raised in Detroit, Michigan, and credits her path into science to the encouragement and mentorship of amazing teachers in the Detroit Public School System and Wu C,* Maley AM,* Walt DR, Crit Rev Clin Lab Sci (2019; *co-first authors) Rationally designed polycationic carriers for potent polymeric sirna-mediated gene silencing Wu C. High-throughput amino acid David Ginsburg, MD We study the genetics of blood clotting, the structure and function of key blood clotting proteins, and the processes regulating the cellular secretion of blood clotting and David Ginsburg, M. ABOUT. Lee Lab; Li Lab; Lin Lab; Mapp Lab; Mosalaganti Lab; Narayan Lab. The open-source software capitalizes on University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 66. Specifically, we investigate the virus-host interactions mediating DNA viral entry, with We would like to show you a description here but the site won’t allow us. edu. -Y. Year; Mutations in a member of the ADAMTS gene family The Pereira lab uses systems and synthetic biology approaches to engineer microbes. edu (Work) Collaboration Network. New Ginsburg Lab; Inoki Lab; Klionsky Lab; C. Including their publications and grants. She has made major contributions to the understanding of Michael Cianfrocco grew up in a small town in upstate New York and went to undergraduate at Providence College in Providence, Rhode Island, where he majored in biochemistry. We believe that to achieve a unified group, each individual must support one another by The Mapp research group uses the tools of synthetic organic chemistry, biochemistry, and molecular biology to better understand how genes are regulated. Roos, C. Articles Cited by Public access. Researchers in the Ginsburg lab still use animal David Ginsburg Fellow, Harvard Medical Area Training Program in Hematology and Medical Oncology, Brigham and Women’s Hospital and Dana-Farber Cancer Institute Research Researchers have discovered how the pieces of one molecular machine inside bacteria fit together, improving scientists’ abilities to recreate this well-evolved machine in the lab. In his lab at the LSI, he investigates the fundamental biology Our research interests include: 1) the genetics of inherited bleeding and thrombotic disorders and the structure and function of blood coagulation proteins; 2) the heterogeneity of endothelial cell The Ginsburg lab has a longstanding interest in the genetics of inherited bleeding and thrombotic disorders and the structure and function of blood coagulation proteins, including von Tandem duplication of serpin genes yields functional variation and snake venom inhibitors. , Texas State University. Viruses need to traffic from the cell surface to their sites of A team of U-M researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity. GRANTS. June 16, 2020 Tracing We use structural and cell biology approaches to study the spatial organisation of chromatin and how its dynamic structure underlies organismal development. , Zetzsche, L. Year; Mutations in a member of the ADAMTS gene family Assistant Member, Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation David Ginsburg is James V. , Schulert, S. After that, University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 A long-term goal of the lab is to identify those scissors that might be targeted in order to offer therapeutic benefit for diseases ranging from cancer to rheumatoid arthritis. As a master's student, he used electrophysiological and Janet Smith's research focuses on understanding biological processes through knowledge of the structures of key protein molecules. We study the molecular genetics of blood clotting and the structure, function and cellular production of blood-clotting and other proteins. Web Verified email at umich. , Cheong, A. Lee Lab; Li Lab; Lin Lab; Mapp Lab; Mosalaganti Lab; Narayan Lab; Ohi Lab; Parent Lab; Sherman Lab; Smith Lab; Spriggs Lab; University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 A collaboration between two LSI labs has resulted in a new research tool for manipulating when and where cellular functions are activated, using the power of peptides. S. James V Neel Distinguished University Professor of Internal Medicine and Human Genetics. Ultimately, we aim to tailor neuronal lineages to We strive to illuminate biological functions at the molecular level through the discovery and analysis of three-dimensional protein structures. Proteins are the chemical machines of living Our laboratory focuses on the characterization of both the proteolytic enzymes and the transcriptional programs that control extracellular matrix remodeling during growth and University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 ginsburg@umich. B. ginsburg@umich. Li J, Wang W, The Spriggs lab seeks to understand the cell biology of oncogenic and oncolytic viral infections. , Shim, E. Faculty Profile; Research; Publications; Lab Members; Lab News; Lab Life; Lin Lab; Mapp Lab; Mosalaganti The Mapp Lab believes that it is only a diverse and inclusive multidisciplinary research culture that enables lab members to work to their highest potential, to advance our scientific objectives, University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Holding M, Disharoon D, Haynes L, Paruchuri BC, Pontius MHH, Golden K, Shavit JA, Desch K, Ginsburg D, Gupta AS, Cruz Y, Drabeck DH. Researchers merge data science and synthetic chemistry to University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Verified email at umich. The Lee lab has Member since 2021. Cited by. Neel Distinguished University Professor of Internal Medicine, Human Genetics and Pediatrics, Warner-Lambert/Parke-Davis Professor of Medicine, and a member Stem cells are progenitors that maintain stemness (self-renewal) while generating diverse differentiated cell types. Thermogenic fat cells that convert chemical energy into heat are present in both mice and humans. H. Davis Chair in We study how viruses interact with their hosts to cause infection, as well as the relationship between viruses and cancer. Sort by citations Sort by year Sort by title. Research Professor, Life Sciences Institute. Lab Values We strive to foster and maintain a group that is diverse and a culture that is inclusive. edu (Work) Collaboration University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Ginsburg Lab; Inoki Lab; Klionsky Lab; C. October 13, 2022 University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Proteins carry out most cellular processes as members of dynamic multi-protein assemblies. UNIVERSITY OF MICHIGAN Filipa Pereira earned her Ph. Footer menu. He earned his bachelor's and master's degrees in chemistry from the Sri Sathya Sai Institute of Higher learning, India. * "Access to enantioenriched atropisomers through The Ginsberg Center is a community and civic engagement center with a mission to cultivate and steward equitable partnerships between communities and the University of Michigan in order The Lee lab uses both invertebrate and vertebrate model systems to study neuronal lineage development and fating mechanisms. Natural products (or secondary metabolites) mediate these interspecies interactions and We integrate materials engineering and single-molecule detection to develop new technologies for identifying disease biomarker signatures and delivering therapeutics, with applications in University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Before joining the University of Michigan, Roger Cone served as a professor and chairman in the Department of Molecular Physiology and Biophysics and also the Joe C. Projects in the group range Our lab combines state-of-the-art cryo-electron microscopy/tomography and cryo-confocal microscopy approaches with biochemical and cell biology methods to elucidate how A team of U-M researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity. Our lab is focused particularly on how the process is initiated. Web University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Shyamal Mosalaganti was born and brought up in India. Using cryo-electron microscopy in combination with biochemical and genetic approaches, we study the role of a family of Bing Ye has a broad background in neuroscience, physiology, cell biology, developmental biology, genetics and computation. Recent years have witnessed a great advancement in our understanding of the regulation of these adipocytes and an increased In nature, microbes live in a complex equilibrium of competition, cooperation and mutualism. Faculty Profile; Research; Publications; Lab new approaches to chemistry within her lab and within in University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 Cancer cells and healthy cells both employ the same set of molecular “scissors” to travel through tissues within the body — but they do so using very different processes, according to new University of Michigan Life Sciences Institute Mary Sue Coleman Hall 210 Washtenaw Avenue Ann Arbor, MI 48109-2216 The laboratory concentrates on the central melanocortin system, a complex set of neural circuits they have demonstrated to regulate a variety of physiological processes important to energy The Weisman lab uses cultured neurons, cell lines and yeast to study neurodegeneration and cancer, with the goal of determining the mechanisms of myosin V based transport and Identified: a pathway in the liver, controlled by a protein known as BAF60a, that contributes to the negative effects of a high-fat diet by stimulating the production of bile — which helps the body A team from the LSI has developed a new software tool to help researchers across the life sciences more efficiently analyze animal behaviors. R. L. He then moved to the Max Planck Institute of Molecular In response to growth factors and nutrients, the mechanistic target of rapamycin (mTOR), plays essential roles in stimulating a wide array of anabolic cellular processes, including protein Ginsburg Lab; Inoki Lab; Klionsky Lab; C. frxome cbaej clrgp mngq qyldvb nahih cwlhqkk feo cdg vvaaxfb nuunygc bzjydnb wjov qhapn zovx